Osmund Saddler is the leader of a cult known as Los Illuminados. This cult consists of the local population of a rural village in Europe that has been converted into Ganados in which Saddler controls due to the Plaga parasites in their bodies. His plan was to kidnap the president’s daughter, Ashley Graham, put the parasite into her and send her back to the US to infect the President, allowing Saddler to begin his conquest of the world. Saddler’s plan was ultimately foiled by Leon S. Kennedy despite his transformation into a multi-legged monstrosity with considerable strength.